The official languages of Mattola are Spanish and English, Spanish is the primary language, and has been spoken since Spanish colonization in the 17th century, English has been spoken since the 19th century, after the United States colonized Mattola.

Spanish is the language for education, transportation, government, and business, as English is also used as a second language, English is usally spoken near the US-Mattola border, and Spanish is spoken all around Mattola.